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Seroquel (quetiapine fumarate) Compared with other Drugs for Other Disorders
Seroquel Basics Seroquel Side Effects How To Take Seroquel Comments Where to Buy Seroquel / Ratings How Seroquel Works & Compares with Other Meds Seroquel for Schizophrenia SSeroquel for Bipolar
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Studies on Seroquel (quetiapine fumarate) for Other Disorders Keep in mind who sponsors the study, as it will tends to make the results more favorable for the med in question (on average 3.6 times more likely, according to a Yale study).
Seroquel for sleep disorders. I could find all of one study: Seroquel vs. placebo - 14 guys, double-blind, either 25 or 100mg of Seroquel (quetiapine fumarate) or the wonder drug Placebo. Seroquel (quetiapine fumarate) was seen to significantly improved sleep induction and continuity under standard and acoustic stress conditions. There were also increases in total sleep time, sleep efficiency, percentage of sleep stage 2 and subjective sleep quality. Basically the stuff knocks you out and keeps you out with quality sleep. The drawback of jumping right to 100mg a night was sudden onset of periodic leg movement. That doesn't surprise me in the least.
Seroquel for anxiety. Again, all of one study: Seroquel + SSRI for anxiety & depression 11 people with depression and an anxiety disorder where an SSRI alone doesn't cut it where given variable amounts of Seroquel (quetiapine fumarate) for nine weeks. By the end of the study 10 out of the 11 saw reduction in both anxiety and depressive symptoms as measured on the Hamilton Rating Scale For Depression, the Hamilton Anxiety scale and the State Anxiety Inventory.
Seroquel for depression: Seroquel vs. Risperdal vs. Zyprexa vs. Geodon to augment antidepressants for treatment-resistant depression Another antipsychotic cage match! 49 people who have ridden a total of 76 horsies on the med-go-round. Here are the results - Zyprexa (olanzapine) is the clear winner with a 57% response rate, followed by Risperdal (risperidone) with 50%, Seroquel (quetiapine fumarate) with 33% and bringing up the rear in a real shock to me, Geodon (ziprasidone) with only 10%. So if your doctor wants to try Zyprexa (olanzapine) combined with an antidepressant first to bring you out of the abyss, don't fret the weight thing. Which sucks less, what you're going through now or a few extra pounds?
See the page on a drugs' efficacy for an explanation of the tests used to evaluate if a medication is any good or not. |
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Dead tree references:
Instant Psychopharmacology 2nd Edition Ronald J. Diamond M.D. © 2002. Published by W.W. Norton
Essential Psychopharmacology Stephen M. Stahl, M.D., Ph. D. © 2000. Published by Cambridge University Press
Essential Psychopharmacology of Antipsychotics and Mood Stabilizers Stephen M. Stahl, M.D., Ph. D. © 2002. Published by Cambridge University Press
Essential Psychopharmacology of Depression and Bipolar Disorder Stephen M. Stahl, M.D., Ph. D. © 2001. Published by Cambridge University Press
A Primer of Drug Action Robert M. Julien, M.D., Ph. D. © 2004. I now use the Tenth Edition. Sometimes that comes up on an Amazon search, usually it doesn't. Published by Worth Publishers
Physicians' Desk Reference Editions 53 & 56 Maria Deutsch & Anu Gupta, Drug Information Specialists, et al. © 1999, 2002. Published by Medical Economics Company.
The Complete Guide to Psychiatric Drugs Edward Drummond, M.D. © 2000. Published by John Wiley & Sons, Inc.
Mosby's 2004 Drug Guide David Nissen PharmD, Editor.© 2004. An imprint of Elsevier. The edition we're using isn't listed on Amazon.
End of books used for this article.
Created Saturday, November 20, 2004
Last updated Saturday, May 15, 2010
Copyright © 2003 - 2006 Jerod Poore. All rights reserved.
Almost all of the material on this site is copyright © 2002, 2003, 2004, 2005 and 2006 Jerod Poore. Except, of course, the PI sheets, those are the property of the drug companies who developed the drugs the sheets are about. And any documents that are written by other people which may be posted to this site will remain the property of the original authors. You cannot reproduce this page or any other material on this site outside of the boundaries of fair use copying without the express permission of the copyright holder. That's usually me, so just ask first. That means if want to print out a few pages to take to your doctor, therapist, counselor, support group, non-understanding family members or something like that - then that's OK to just do. Go for it! Please. As long as you include this copyright notice and the following disclaimer, I'm cool with it.
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"Everything is true, nothing is permitted." - Jerod Poore
